Biomedical Sciences
*410.
Research in Medical Sciences.
(1-3 to a maximum of 9 ∆)
Laboratory research in the medical sciences for undergraduate students.
Restriction: permission of instructor
{Offered upon demand}
501.
Fundamentals for Graduate Research.
(1)
This course provides first year students with information for making an educated choice of a dissertation research advisor, of various teaching and research resources and facilities, and teaching and communication skills.
{Fall}
505.
Special Topics in Biomedical Sciences.
(1-6 to a maximum of 48 ∆)
This course provides a format to teach current information in a variety of rapidly advancing areas of biomedical research which are not now provided by existing courses. Subject area varies depending on the need for education in a particular area and the faculty member involved.
Restriction: permission of instructor.
{Offered upon demand}
506.
Special Topics in Biomedical Research.
(1-2 to a maximum of 3 ∆)
In this course, first year graduate students will participate in research with potential thesis or dissertation mentors and gain first-hand experience in a variety of techniques and approaches to biological problems.
Offered on a CR/NC basis only.
507.
Advanced Molecular Biology.
(4)
(Also offered as BIOL 581)
The course covers the structures and functions of nucleic acids and proteins, mechanisms and macromolecular synthesis and principles of enzymology.
Prerequisite: organic chemistry, one semester of cell biology or biochemistry.
{Fall}
508.
Advanced Cell Biology.
(4)
(Also offered as BIOL 582)
Course covers advanced topics in cell biology, including microscopy, the nucleus, protein and membrane trafficking, cytoskeleton signal transduction, cell cycle and division and extracellular matrix.
Prerequisite: 507
{Fall}
509.
Principles of Neurobiology.
(3)
This course covers cellular structure of neurons and glia, the electrical properties of neurons, intercellular communication, and the formation, maintenance and plasticity of chemical synapses.
510.
Physiology.
(3)
Course in regulatory and systems biology, and cardiovascular and pulmonary biology.
Prerequisite: 508.
{Spring}
511L.
Intensive Introductory Biochemistry I.
(4)
Anderson
(Also offered as BIOC 545L)
An introduction into the physical and chemical properties of proteins and enzymes; enzymatic catalysis; structure, synthesis and processing of nucleic acids and proteins; structure and control of genetic material.
{Fall}
512L.
Intensive Introductory Biochemistry II.
(4)
(Also offered as BIOC 546L)
An introduction to intermediary metabolism and hormonal control of catabolic and anabolic pathways.
Prerequisite: 511L
{Spring}
514.
Immunobiology.
(3)
This is a comprehensive, fundamentals-based immunology course for graduate students in the biomedical sciences or related fields. The course will have a problem-based component that will introduce students to experimental design in immunological research.
Prerequisite: graduate status.
{Spring}
515.
Cancer Biology.
(3)
Fundamental elements of cancer development and progression will be the focus of this course. Basic biochemical and genetic mechanisms of tumorigenesis, including genomic instability, principles of tumor cell invasion and growth dysregulation will be emphasized.
516.
Molecular Genetics and Genomics.
(3)
Covers genetic and genomic approaches in model organisms (prokaryotes, fungi, worms, mouse and fruit flies) and humans to study biological processes at the molecular, cellular, tissue, organism, population and evolutionary levels. Provides an introduction to bioinformatic and computational methods used in such studies.
Prerequisite: 507, 508.
522.
Experimental Design and Methods in Molecular and Cellular Biosciences.
(3)
This case-based course is intended for first year graduate students and focuses on practical issues of how to design, plan and conduct scientific studies through appropriate use of experimental methods and data analysis.
525.
Cell and Molecular Basis of Disease Journal Club.
(2 to a maximum of 4 ∆)
Course offers new graduate students experience in oral presentation skills, experience in reading and discussing scientific literature and exposure to research seminars. Student led discussions partner with weekly Cell and Molecular Basis of Disease Seminar.
{Fall, Spring}
530.
Cell and Molecular Basis of Disease Seminar.
(1 to a maximum of 5 ∆)
The Cell and Molecular Basis of Disease Seminar is a cross-cutting, interdepartmental seminar series offered for graduate credit. Weekly seminars are presented by preeminent scientists on a wide variety of broadly relevant research topics.
{Fall, Spring}
532.
Neurochemistry.
(3)
(Also offered as BIOC 521)
An introduction to neurochemistry and neuropharmacology, with heavy emphasis on student participation, by reading and evaluating current publications.
Restriction: permission of instructor
{Fall, even years}
533.
Neurophysiology and Neuroanatomy.
(4)
Provides a background and understanding of the structure and function of the mammalian nervous system. The course includes both lectures and laboratory experiences.
Prerequisite: 509.
{Fall, odd years}
535.
Neuroscience Seminar.
(1 to a maximum of 10 ∆)
Weekly presentation of current topics in clinical neuroscience and in neuroscience basic research.
537.
Advanced Topics in Neuroscience.
(1-3 to a maximum of 9 ∆)
Study Projects in the literature of Neuroscience.
Restriction: permission of instructor.
540.
University Teacher Training.
(2)
An introduction to the principles of how people learn and methods of teaching and assessment. Special workshops provide hands-on experience with effective lecture preparation and tutorial group facilitation for problem-based learning.
Restriction: permission of instructor.
541.
Teacher Training Workshops.
(1-2, may be repeated twice ∆)
Workshops emphasizes skill development in education theory and curriculum development or student assessment and feedback through didactic lectures and hands-on experience. Workshops are led by School of Medicine Teacher Education and Development (TED) Office and the Teaching Assistant Resource Center (TARC) faculty.
Prerequisite: permission of instructor.
542.
Teaching Assistant Practicum.
(1-4, may be repeated three times ∆)
BSGP students enrolled in this course earn course credit for serving as teaching assistants. The number of credits is determined by the number of contact hours. Arrangements are made on an individual basis.
Prerequisites: 540 or 541.
543.
Independent Education Immersion for Teaching Scholars.
(1-4, may be repeated once ∆)
Emphasizes skill development as an independent instructor. Requires development or implementation of independent teaching or educational project. Scholars are evaluated on teaching materials, oral and written communication skills, and project design and tool development. Arrangements for service as course instructor are made on an individual basis.
Prerequisite: 542.
Restriction: permission of instructors.
544.
Human Anatomy for Basic Scientists.
(4)
Biomedical Sciences Graduate Program students may take the lecture and laboratory portions of the Human Structure, Function, and Development block of the SOM curriculum, making them eligible for teaching assistantships in the block in subsequent years.
{Spring}
Restriction: permission of instructor.
548.
Biochemistry and Molecular and Cellular Biology Seminar.
(1 to a maximum of 10 ∆)
{Fall, Spring}
553.
Biochemistry of Disease I.
(1-3)
(Also offered as BIOC 563)
Five 3-week topics, each designed to develop some basic concepts of biochemistry, cell and molecular biology in the context of disease states.
{Fall}
554.
Biochemistry of Disease II.
(1-3)
(Also offered as BIOC 564)
Five 3-week topics, each designed to develop some basic concepts of biochemistry, cell and molecular biology in the context of disease states.
{Spring}
555.
Problem-Based Research Bioethics.
(1)
This is a problem-based discussion course on topics in bioethics such as publication credits and authorships; conflict of interest and fraud, scientific misconduct, human genomics and other relevant issues.
{Fall}
556.
Research Design for Clinical and Translational Research.
(1 to a maximum of 6 ∆)
This course will introduce the variety of study designs that are used to conduct clinical and translational research, including qualitative, observational, experimental, quasi experimental, non-experimental and mixed methods designs.
Restriction: permission of course director.
557.
Measurement in Clinical and Translational Research.
(1 to a maximum of 6 ∆)
This course will cover qualitative and quantitative instrument design, construction, theory, and implementation; qualitative data analysis and interpretation; assessment of measurement reliability, validity, accuracy, precision, specificity and sensitivity.
Restriction: permission of course director.
558.
Study Implementation and Project Management in Clinical and Translational Research.
(1 to a maximum of 6 ∆)
This course trains researchers in the management of clinical and translational research studies, including organizational processes to implement and conduct a funded research study, with financial, personnel, and business management and compliance issues.
Restriction: permission of course director.
559.
Biostatistics in Clinical and Translational Research.
(1 to a maximum of 6 ∆)
Overview of the basic principles and methods of biostatistics designed specifically for clinical and translational research scientists. Computer software is used to analyze clinical and translational data sets.
Restriction: permission of course director.
560.
Current and Emerging Technologies in Clinical and Translational Research.
(1 to a maximum of 6 ∆)
Course covers key biomedical research technologies currently in use for studies at the cellular and molecular, clinical and community levels, concentrating on the advantages and disadvantages of technologies for application to specific translational research studies.
Restriction: permission of course director.
561.
Patient Outcomes in Clinical and Translational Research.
(1 to a maximum of 6 ∆)
Overview health care economics and patient outcomes research, including public policy issues associated with the rising cost of health care, patient-reported outcomes, clinical outcomes, and economic outcomes, and evaluation of patient outcomes research.
Restriction: permission of course director.
562.
Epidemiology in Clinical and Translational Research.
(1 to a maximum of 6 ∆)
Course introduces the student to Epidemiology, the study of causes, distribution and control of disease in populations. A methodology to identify risk factors for disease and to determine optimal treatment approaches.
Restriction: permission of course director.
563.
Conducting Clinical and Translational Research within Health Care Systems.
(1 to a maximum of 6 ∆)
This course will cover the dimensions of a variety of health care systems and settings and discuss potential areas for investigation; challenging learners to consider the opportunities where research can contribute to system improvements.
Restriction: permission of course director.
564.
Biomedical Informatics in Clinical and Translational Research.
(1 to a maximum of 6 ∆)
This course covers information technology tools and biomedical informatics strategies to optimize collection, storage, retrieval, and intra-/inter-institutional sharing of quantitative and qualitative data in support of clinical and translational research.
Restriction: permission of course director.
565.
Cultural Competence in Clinical and Translational Research.
(1 to a maximum of 3 ∆)
This course covers the impact of culture including values, tradition, history and institutions, sources of health care disparities, how culture influences in the way patients respond to medical services, prevention and physician delivery of services.
Restriction: permission of course director.
566.
Grantsmanship in Clinical and Translational Research.
(1 to a maximum of 3 ∆)
Grant preparation fundamentals focused on writing and submitting a competitive research or fellowship application that meets prevailing guidelines, addresses an important hypothesis-driven research question and is responsive to critical feedback and review.
Restriction: permission of course director.
567.
Biomedical Ethics and Regulatory Compliance in Clinical and Translational Research.
(1 to a maximum of 6 ∆)
History and development of biomedical ethics in theory and practice within health care, tenets of autonomy, beneficience, non-malfeasance and justice as they pertain to human clinical research and the development of health care public policy.
Restriction: permission of course director.
568.
Seminar in Clinical and Translational Research.
(1 to a maximum of 3 ∆)
Includes integration and synthesis of concepts integral to clinical and translational research, providing problem-based and cross-cutting case studies for analysis/discussion, networking opportunities and a platform to demonstrate competencies.
Restriction: permission of course director.
576.
Molecular and Cellular Pharmacology.
(3)
Basic principles and recent advances underpinning modern molecular and cellular pharmacology. Topics include receptor theory, drug metabolism and biotransformation, pharmacogenomics, receptors and signal transduction, rationale drug design and selected topics in organ-system based pharmacology.
Prerequisite: 507, 508.
{Spring}
580.
General Toxicology I.
(3)
An in-depth introduction to the basic principles and concepts of toxicology. Categories of chemicals causing toxic effects, the manner of exposure to toxic substances, the environmental and biological effects, and the laws and regulations will be considered.
581.
Colloidal Nanocrystals for Biomedical Applications.
(3)
(Also offered as ECE, NSMS 581)
Intended for students planning careers combining engineering, materials science, and biomedical sciences. Covers synthesis, nanocrystals characterization, biofunctionalization, biomedical nanosensors, FRET-based nanosensing, molecular-level sensing/imaging, and applications in cell biology, cancer diagnostics and therapy, neuroscience, and drug delivery.
583.
Pathology Seminar.
(1 to a maximum of 6 ∆)
Weekly presentations of current topics in pathology.
{Summer, Fall, Spring}
590.
Topics in Biochemistry.
(1-3 to a maximum of 9 ∆)
Restriction: permission of instructor.
594.
Topics in Environmental Disease.
(1-3 to a maximum of 3 ∆)
Advanced readings in topics relating to toxicology and environmental disease, including areas such as chemical teratogenesis, reactive oxygen species, respiratory toxicology, receptor-medicated toxicology and environmentally induced cancer.
Prerequisite: PHRM 580.
{Fall, Spring}
599.
Master’s Thesis.
(1-6, no limit ∆)
Offered on a CR/NC basis only.
605.
Membrane Trafficking Seminar.
(1 to a maximum of 4 ∆)
A weekly journal club style course for advanced graduate students to participate in journal club presentations and discussion of current literature in the field of intracellular membrane trafficking.
{Fall, Spring}
615.
Signal Transduction and Cell Adhesion Seminar.
(1, no limit ∆)
Weekly presentation of current topics in signal transduction and cell adhesion research.
{Fall, Spring}
616.
Molecular Virology.
(3)
Fundamental principles related to interactions of animal viruses with host cells. Topics include virus chemical and physical properties, virus classification, virus cultivation and assay, viral replication and morphogenesis, persistent infections, viral oncology and other pertinent subjects.
Pre- or corequisite: 511L, BIOL 450, BIOL 456.
Restriction: permission of instructor.
{Fall, odd years}
620.
Molecular Genetics and Microbiology Seminar.
(1 to a maximum of 3 ∆)
Weekly presentations of current topics in Immunology and Microbiology.
{Fall, Spring}
624.
Proteomics.
(3)
This course is designed to probe for knowledge of the immune system by looking at molecular mechanisms responsible for the generation and regulation of immune responses.
Prerequisite: introductory course in immunology, 512L.
{Alternate years}
625.
Advanced Topics in Immunology & Microbiology.
(1-3 to a maximum of 9 ∆)
May be taken three times to a maximum of 9 credit hours.
Prerequisite: biochemistry, general microbiology or equivalent.
{Offered upon demand}
642.
Advanced Topics in Cell Biology.
(1-3 to a maximum of 9 ∆)
An advanced graduate-level course in which current information in a variety of rapidly advancing areas of cell biology research is taught. This course is usually taught in seminar format. Subject area varies depending on the need for education in a particular area and the faculty member involved.
Restriction: permission of instructor.
{Summer, Fall, Spring}
646.
Advanced Topics in Molecular Biology.
(1-3 to a maximum of 9 ∆)
An advanced graduate-level course in which current information in a variety of rapidly advancing areas of molecular biology research is taught. This course is usually taught in seminar format. Subject area varies depending on the need for education in a particular area and the faculty member involved.
Restriction: permission of instructor.
{Summer, Fall, Spring}
652.
Immunopathogenesis of Infectious Diseases.
(2)
This course will cover basic models of immunopathogenesis and immune evasion mechanisms using well-characterized infectious disease models. Topics will include host mechanisms of microbial clearance, immune-mediated inflammation and pathological effects of pathogens and microbial mechanisms of avoiding host attacks.
657.
Advanced Topics in Cellular and Systems Physiology.
(1-3 to a maximum of 9 ∆)
This is an advanced graduate level course covering current, rapidly changing topics in physiology. Taught in a combination lecture/seminar format, the subject area varies depending on the expertise of the faculty member(s) involved.
Restriction: permission of instructor.
659.
Regulatory and Systems Biology Seminar.
(1 to a maximum of 10 ∆)
Weekly presentations of current topics in regulatory and systems biology.
672.
Structure and Function of the Cell Nucleus.
(3)
A survey of experimental approaches to study the relationship between nuclear structure and function and eukaryotic gene expression. Students must reserve a place in the course by contacting the instructor.
Prerequisite: (507 and 508) or (BIOL 420 and 449).
677.
Muscle Cell Biology.
(1 to a maximum of 6 ∆)
An in-depth overview of muscle structure and function, muscle cell gene expression, and neuromuscular diseases.
Restriction: permission of instructor.
695.
Research in Basic Medical Sciences.
(1-6, no limit ∆)
699.
Dissertation.
(3-12, no limit ∆)
Offered on a CR/NC basis only.
701.
Post Doctoral Research.
(1-6 to a maximum of 6 ∆)
A course in techniques, laboratory methods and administration.
May be taken nine times to a maximum of 54 credit hours.
Offered on a CR/NC basis only.
{Summer, Fall, Spring}
