Pharmaceutical Sciences Graduate Program inquiries should be addressed to the College of Pharmacy Office of Student Services, MSC09 5360, 1 University of New Mexico, Albuquerque, NM 87131. Applications to the Pharmaceutical Sciences Graduate Program use the Office of Graduate Admissions online or paper application for domestic applicants. Information and instructions for completing this form are available at the http://www.unm.edu/~grad/admissions/admissions.html Application materials for international students can be found through The University of New Mexico’s Office of International Admissions http://www.unm.edu/preview/na_intlgrad.htm.
Students wishing to pursue a graduate degree in Pharmaceutical Sciences must meet the general requirements for admission to graduate studies outlined elsewhere in this catalog. In addition, each concentration of study has prerequisites for admission that are described below.
The Committee on Studies determines the Programs of Study for graduate students for each concentration. In general, this program consists of core and elective course work required of all students. However, in some cases the Committee on Studies may approve a Program of Study that takes advantage of previously completed course work or provides interdisciplinary training of interest to particular students. More specific information on the programs is given below.
This is a program of study and research leading to a M.S. and/or Ph.D. degree emphasizing the social, psychosocial, political, legal, historical and economic factors that impact on the use, non-use and misuse of drugs. It emphasizes human behavior in health illness, cultural determinants, health service systems organization, finance and economics. Individuals examine the societal systems in which patients, pharmacists and other health care practitioners interact, behave, perform, generate revenues, provide services and are educated. They generate knowledge about man as a social, cultural, psychological and biological being, as well as the intervention and effect of health care systems upon man and the economics of pharmacy services. Study and research training in this discipline prepares individuals with the background and problem solving skills to evaluate and design systems for the delivery of pharmaceutical systems and to apply behavioral and social interdisciplinary theories to the study of pharmacy practice. Two emphases areas are available:
A program leading to an M.S. degree in Pharmaceutical Sciences with a concentration in radiopharmacy is offered to individuals who have received a professional degree in pharmacy or a B.S. in a health-related science. The primary mission of the Radiopharmacy Education Program is to provide a comprehensive training experience that affords individuals the opportunity to acquire the scientific knowledge, technical skills, and professional judgement required to promote patient care through assurance of the safe and efficacious use of radiopharmaceuticals and ancillary medications for diagnosis and therapy. In order to best accomplish this mission, it is necessary to develop professionals who can solve problems, think logically and work independently or in collaboration to conduct research that will add to the knowledge base in nuclear medicine and radiopharmaceutical science.
Moreover, nuclear pharmacy is practiced in countries all around the world. Not only are U.S. pharmacists traveling to these countries to meet their health care needs, but pharmacists from these countries are also seeking opportunities to become competently trained nuclear pharmacy practitioners in order to return to their native lands. To maintain its reputation as a premier nuclear pharmacy education program, The University of New Mexico College of Pharmacy must seek to address the idiosyncrasies and needs of nuclear pharmacy on an international scale.
The comprehensive nature of the program is related to the fact that information is made available in a variety of ways. The program therefore is able to achieve the following goals:
The entire pharmacy profession, including the specialty of nuclear pharmacy, is an applied science. However, nuclear pharmacy, even more so than general pharmacy practice, relies upon a firm grounding in multiple basic sciences. To practice nuclear pharmacy, you must be able to extemporaneously compound and test a wide range of radioactive
medications, develop and enforce adequate radiation protection measures for one’s self and coworkers, meet the demand of numerous regulators and troubleshoot a variety of imaging pitfalls and artifacts and also provide patient care in a setting that is foreign to most pharmacists. Therefore, to achieve an optimal learning environment for nuclear pharmacy, it is essential to have an appropriate blending of the clinical sciences with multiple basic sciences.
College level organic chemistry, physics and mathematics through calculus are prerequisites for entry into the program. In addition, general requirements for admission to the program are specified on earlier pages of this catalog. Didactic and laboratory course work, research leading to a thesis (Plan I) or non-thesis (Plan II) degree and an opportunity for experience in radiopharmacy practice are components of the program. General requirements for completion of the degree are specified on earlier pages of this catalog. The student’s program will be developed and is supervised by a Committee on Studies.
Toxicology and Pharmaceutical Sciences encompasses a broad range of scientific disciplines that are critical to the discovery and development of new drugs and therapies, including drug design and chemical biology, pharmaceutics and drug delivery, radiopharmaceutical target imaging, and pharmacokinetics, pharmacodynamics, drug metabolism, pharmacogenomics and toxicology. The group is focused on developing outstanding scientists through training in the biomedical and pharmaceutical sciences and disease processes. Specific strengths of the program include gene-environment interactions and the mechanisms by which exposure to environmental hazards adversely affect living organisms. Highly innovative programs such as the New Mexico Center for Environmental Health Sciences, the New Mexico Center for Isotopes in Medicine, the UNM Biomedical Research and Integrative Imaging (BRaIN) Center offer excellent opportunities for collaborative basic and translational research among faculty in the College of Pharmacy, School of Medicine, and Lovelace Respiratory Research Institute.
For those students interested in obtaining an M.S. or Ph.D., the UNM Biomedical Sciences Graduate Program http://hsc.unm.edu/som/research/brep/ offers these degrees with a focus in one of six content areas, including Toxicology and Pharmaceutical Sciences. During the first year of study, students take core courses through the UNM Biomedical Sciences Graduate Program. This core course work emphasizes basic concepts in biochemistry, molecular biology, cell biology, and reading in the biolmedical sciences literature. In the second and subsequent years, students are required to take Molecular and Cellular Pharmacology and General Toxicology, followed by advanced courses in pharmaceutical sciences and toxicology and other topics related to the student's research. These courses may be further supplemented with elective courses chosen by the student and their Committee on Studies.
These programs are designed to develop outstanding M.S. and Ph.D. research scientists by providing a firm foundation of knowledge in biomedical sciences augmented by an emphasis on research-based, experimental approaches to learning. Areas of research are diverse and current research interests can be found on the program’s website. Typically, students graduating from this program have gone on to careers in academia, the pharmaceutical industry, government regulatory agencies, and biotechnology firms.
Courses
PHRM 496.
Topics in Pharmacy.
(1 to a maximum of 3 ?)
Restriction: permission of instructor.
PHRM 497.
Problems in Pharmacy.
(1-5, no limit ?)
Research and library problems in some phase of pharmacy. Not for professional students in the College of Pharmacy curriculum.
Restriction: permission of instructor.
PHRM 498.
Problems in Pharmacy.
(1-5, no limit ?)
Research and library problems in some phase of pharmacy. Not for professional students in the College of Pharmacy curriculum.
Restriction: permission of instructor.
PHRM 511 / 773.
Nuclear Pharmacy Instrumentation.
(3)
Structure and properties of atoms, radiation and radioactive decay, production of radionuclides, interactions of radiation with matter, with emphasis on instrumentation for radiation detection and measurement in a nuclear pharmacy or nuclear medicine environment.
Restriction: permission of instructor.
PHRM 512 / 774.
Radiopharmaceutical Chemistry.
(1)
Introduces undergraduate students to inorganic chemistry as applicable to radiopharmaceuticals.
Prerequisite: CHEM 302 or equivalent.
Restriction: permission of instructor.
PHRM 514.
Basics of Nuclear Pharmacy Practice.
(2)
Restriction: permission of instructor.
PHRM 516 / 776.
Radiopharmacology.
(3)
Study of the physicochemical characteristics of radiopharmaceuticals; kinetics of radiopharmaceuticals; structure-distribution relationships of radiopharmaceuticals; considerations in the design of new radiopharmaceuticals.
Restriction: permission of instructor.
PHRM 518.
In-Vitro Radiotracer Procedures.
(2)
This course will provide the principles of in-vitro methods such as radioimmunoassay, autoradiography, ferrokinetics, radiometic assay, x-ray fluorescence and neutron activation analysis.
Restriction: permission of instructor.
PHRM 519L.
Instrumentation and In Vitro Lab.
(2)
Practical experience in in-vitro radiotracer techniques and instrumentation in nuclear pharmacy.
Restriction: permission of instructor.
PHRM 521.
Radiopharmaceutics.
(2)
Study of the physicochemical characteristics of radiopharmaceuticals; kinetics of radiopharmaceuticals; structure-distribution relationships of radiopharmaceuticals; considerations in the design of new radiopharmaceuticals.
Restriction: permission of instructor.
PHRM 523.
Clinical Nuclear Medicine.
(1)
The utility of nuclear medicine procedures in the diagnostic work-up of patients with various diseases is presented using case studies illustrated by data obtained from multiple imaging modalities.
Prerequisite: (511 or 773) and BIOL 238.
PHRM 545-546.
Pharmacy and Its Environment.
(3, 3)
Exploration of the cultural foundations of pharmacy. Development of the present state of practice. Social and psychological factors in drug use. Role of the pharmacist as a health practitioner.
PHRM 547.
Pharmacy Practice Research.
(3)
An introduction for graduate students in pharmacy administration to issues in pharmacy practice research. Research process, methods, measurement, tools, designs and ethics.
PHRM 548.
Ethics Clinical Trials/Informed Consent.
(2)
The study of the history, ethical versus scientific methodological conflicts, and other issues that are generated by the conduct of randomized controlled clinical trials using human beings.
PHRM 549.
Regulatory Issues in Clinical Trials.
(2)
The study of federal regulations and guidelines that govern the planning and conduct of randomized controlled clinical trials in humans with drugs and devices.
PHRM 550.
Pharmacoeconomics and Patient Outcomes Research in Medicine.
(3)
The study of the economic results associated with pharmaceutical treatment or care and consequences of health care, including clinical (healing, disease/symptom remission), humanistic (satisfaction, health-related quality of life, societal utility), and economic (costs/savings).
PHRM 576.
Molecular and Cellular Pharmacology.
(1 [3])
Basic principles and recent advances underpinning modern molecular and cellular pharmacology. Topics include receptor theory, drug metabolism and biotransformation, pharmacogenomics, receptors and signal transduction, rationale drug design and selected topics in organ-system based pharmacology.
Prerequisite: BIOM 509 or BIOM 510.
{Fall}
PHRM 580.
General Toxicology.
(2 [3])
An in-depth introduction to the basic principles and concepts of toxicology. Categories of chemicals causing toxic effects, the manner of exposure to toxic substances, the environmental and biological effects, and the laws and regulations will be considered.
PHRM 591.
Seminar in Administrative Pharmacy.
(1, no limit ?)
This course will give the students experience in organizing and presenting their thoughts and interpretations on a selected subject. The seminar will provide the student with an opportunity to develop writing and formal oral presentation skills.
Restriction: permission of instructor.
PHRM 592.
Seminar in Radiopharmacy.
(1, no limit ?)
Each masters candidate will be required to present a seminar on a topic of choice approved by his/her supervisor or selected by the supervisor.
Restriction: permission of instructor.
PHRM 593.
Seminars in Toxicology.
(1, no limit ?)
Research seminars on current topics in Toxicology will be presented by students and faculty from within UNM and from invited speakers outside of UNM.
Restriction: permission of instructor.
PHRM 594.
Topics in Environmental Disease.
(1-3 to a maximum of 4 ?)
Advanced readings in topics relating to toxicology and environmental disease, including areas such as chemical teratogenesis, reactive oxygen species, respiratory toxicology, receptor-medicated toxicology and environmentally induced cancer.
Prerequisite: 580.
Restriction: permission of instructor.
{Fall, Spring}
PHRM 597.
Research Problems in Pharmaceutical Sciences.
(1-6, no limit [1-5 to a maximum of 12] ?)
Research in pharmaceutical sciences.
Restriction: permission of instructor.
PHRM 598.
Topics in Pharmaceutical Sciences.
(1-3 to a maximum of 4 ?)
Advanced readings in topics relating to the pharmaceutical sciences in the areas of hospital pharmacy, pharmacy administration, radiopharmacy or toxicology.
Restriction: permission of instructor.
PHRM 599.
Master?s Thesis.
(1-6, no limit ?)
Offered on a CR/NC basis only.
PHRM 699.
Dissertation.
(1-9, no limit ?)
Offered on a CR/NC basis only.
PHRM 701.
Pharmaceutics I. (Pharmaceutical Dosage Forms I) .
(3)
Study of pharmaceutical dosage forms and relevant physico-chemical and biopharmaceutical principles. Introduction to the metrology and calculations involved in the compounding and dispensing of pharmaceutical preparations.
PHRM 702.
Pharmaceutics II.
(3)
Continuation of 701.
PHRM 703L.
Pharmaceutical Care Lab I.
(3)
Introduction to the “languages and tools” used in contemporary pharmacy practice. Emphasis on calculations, communication, drug information, product formulation, and problem-solving.
PHRM 704L.
Pharmaceutical Care Lab II.
(3)
Continuation of 703L with additional emphasis on patient information, assessment and monitoring; prescription processing; patient counseling; drug administration techniques; laboratory and home diagnostics tests; consult notes; and professional presentations.
PHRM 705.
Pathophysiology.
(4)
Pathological consequences of disease states, including clinical presentation and histological findings presented by organ systems. Includes an introduction to medical terminology.
PHRM 706.
Foundations of Drug Action.
(3 [4])
An introduction to the molecular and chemical mechanisms of therapeutic agents. Topics include biochemical processes and drug targets, gene regulation and expression, cell signaling, and drug absorption, distribution, metabolism, and excretion processes.
PHRM 707.
Pharmacy and Health Care Delivery.
(3 [2])
Marketing and economic concepts of pharmacy practice, with a focus towards marketing of pharmaceutical services and products, pharmacy finance and economics in operations, pharmacoeconomics and decision-making.
PHRM 709.
Introduction to Pharmacy Practice.
(1)
An introduction to the profession of pharmacy including career options, ethical principles, the responsibilities of being a health professional, the professional literature, and personal portfolio development.
PHRM 710.
Mechanisms of Drug Action I.
(5)
First in a series of courses addressing principles of pharmacology, medicinal chemistry and biochemical mechanisms of drug action and toxicity. This section will specifically cover basics of drug metabolism and the pharmacology, structure-activity relationships (SAR), toxicology and elimination of drugs that act upon the autonomic nervous system.
PHRM 713.
Pharmaceutical Calculations.
(1)
This course will introduce students to the knowledge and skills of fundamental mathematical calculations utilized in pharmacy practice.
PHRM 715.
Pathophysiology II.
(4)
A continuation of Pharmacy 705.
PHRM 717.
Introductory Pharmacy Law.
(1)
An introduction to the Federal and New Mexico laws that relate to the practice of pharmacy.
PHRM 718L.
Pharmaceutical Care Lab III.
(2)
Continuation of 704L. Activities parallel topics in concurrent self-care therapeutics and literature evaluation courses. Emphasis on patient assessment, care planning, and monitoring; critical literature appraisal; and written communication skills.
PHRM 719.
Self-Care Therapeutics.
(3)
A pharmacotherapeutics course studying the use of non-prescription drugs, supplies, and herbal medicinals with emphasis on the pharmacist’s role as advisor, communicator, and educator to patients.
PHRM 720.
Introduction to Nuclear Pharmacy.
(2)
This course provides an overview of nuclear pharmacy as a practice specialty: contributions of the nuclear pharmacist and application of radioactive tracer techniques in the diagnosis and treatment of disease will be reviewed.
PHRM 726.
Pharmacokinetics and Biopharmaceutics.
(3)
An introduction to the influence of absorption, distribution, metabolism, and excretion on the time course of drug levels in body and in understanding how changes in these processes affect the outcomes of drug therapies.
PHRM 728.
Pharmacy Informatics and Research.
(3)
An examination of the structure of the biomedical literature and research with emphasis on the recognition, evaluation and application of different study types and the data they produce.
PHRM 729.
Sterile Products.
(2)
The administrative (i.e., procedural) and pharmaceutical (i.e., preparation and dispensing) aspects of pharmacy-initiated (i.e., commercially-available and extemporaneously-prepared) sterile products.
PHRM 731.
Mechanisms of Drug Action II.
(5)
Continuation of 710 addressing pharmacology, toxicology, SAR and elimination of prototypes in specific drug classes.
PHRM 732.
Mechanisms of Drug Action III.
(5)
Continuation of 710 and 731 addressing pharmacology, toxicology, SAR and elimination of prototypes in specific drug classes.
PHRM 733L.
Pharmaceutical Care Lab IV.
(2)
Continuation of 718L. Activites parallel topics in concurrent pharmacotherapy drug course, with emphasis on patient assessment, care planning, and monitoring; self-care practices and verbal communication skills.
PHRM 734.
Comprehensive Diabetes Elective.
(2)
This course will provide the student with a multidisciplinary foundation in the principles of diabetes management. The student will develop knowledge and ability to assess, manage, educate and monitor patients with diabetes.
PHRM 735.
Substance Abuse Elective.
(2)
This course emphasizes the most important themes and concepts in the field. Lectures/presentations will cover major categories of drug abuse (Opioids, Marijuana, Stimulants, Hallucinogenics, CNS depressants, Performance-enhancing drugs, OTC drugs, Herbals, Plants, and Tobacco/Caffeine/EtOH).
PHRM 736.
Introduction to Pharmacogenomics.
(2)
An introduction to how inherited variations in genes dictate drug response. Topics covered include basic principles of medical genetics, chemotherapy improvement through pharmacogenomics, as well as the ethical, legal, and social impact of pharmacogenomics.
PHRM 739.
Pharmacotherapy I.
(6)
Introduces students to a systematic approach to patient-centered pharmaceutical care, emphasizing patient assessment, problem-solving, communication, and counseling skills. Begins pharmacotherapy sequence.
PHRM 740.
Self-Selected Supplementary Pharmacy Education.
(1-2 to a maximum of 2 ?)
This course is designed to allow students to self-identify areas for supplemental pharmacy education. Student will select and complete ACPE-approved continuing education programs.
PHRM 748.
Research Project (Initial).
(1)
Student formulates hypothesis for research project and establishes methodologies for completion under guidance of faculty. Research project approved by committee. Offered on a CR/NC basis only
.
PHRM 751.
Pharmacotherapy II.
(6)
Study of the therapy of common disease states by organ systems integrating the concepts from pathophysiology, pharmacology, biopharmaceutics, pharmacokinetics and pharmacoeconomics in the treatment of patients. Fully develops the concept of pharmaceutical care or how to provide the most cost-effective care of a patient including over-the-counter and natural remedies.
PHRM 752.
Pharmacotherapy III.
(6)
Continuation of 751.
PHRM 755.
Seminar in Pharmacy.
(1 to a maximum of 2 ?)
Offered on a CR/NC basis only.
PHRM 756.
Safe Medication Practices.
(2)
A study of the existence of medication errors, reasons for these errors and suggested methods to prevent them from occurring.
PHRM 758.
Research Project.
(1)
Student completes research project in final year. Up to four students may work collaboratively on one project.
Offered on a CR/NC basis only.
PHRM 759.
Advanced Law and Ethics.
(2)
Emphasis given to statues and regulations regulating the practice of pharmacy and distribution of drugs including the New Mexico Pharmacy Practice Act. Class discussion will include the application of ethics to situations in health care.
PHRM 760.
Pharmacy Healthcare Management and Economics.
(3)
Provides students with an overview of the principles of marketing of pharmaceutical services, managed care pharmacy, pharmacoeconomics and outcomes research, and personnel management.
PHRM 761.
Introduction to Managed Care Pharmacy Practice.
(2)
Issues critical to managed care pharmacy practice will be introduced such as: disease management, formulary management, drug utilization review, benefit design and contracting, Medicare and Medicaid, distribution systems and network management, quality improvement, health informatics.
PHRM 762L.
Pharmaceutical Care Lab V.
(2)
Continuation of 733L, activities parallel concurrent pharmacotherapy courses. Emphasis on patient assessment, care planning, and monitoring.
PHRM 764.
Emerging Technologies in Pharmaceutical Care.
(1)
Provides students with an understanding of the principles of biotechnology, pharmacogenomic, and other state of the art therapies in pharmacy.
PHRM 765L.
Pharmaceutical Care Lab VI.
(2)
Continuation of 762L, activities parallel concurrent pharmacotherapy courses. Emphasis on patient assessment, care planning, and monitoring.
PHRM 766.
Public Health in Pharmacy.
(2)
This course provides students with an introduction to public health from a pharmacy perspective.
Restriction: admitted as PharmD student.
PHRM 770.
Advanced Pharmacy Practice Experience.
(2-4 to a maximum of 36 ?)
Consist of four-week clinical experiences (40 hours/week) where students provide direct pharmaceutical care to patients.
PHRM 771.
Introductory Community Pharmacy Practice Experience.
(2 to a maximum of 4 ?)
A four-week (40 hours/week) directed dispensing pharmacy experience. Students will be exposed to ambulatory patient care in a community pharmacy setting.
Offered on a CR/NC basis only.
PHRM 772.
Introductory Institutional Pharmacy Practice Experience.
(2 to a maximum of 4 ?)
A four-week (40 hours/week) directed dispensing pharmacy experience. Students will be exposed to in-patient care in an institutional pharmacy setting.
Offered on a CR/NC basis only.
PHRM 773 / 511.
Nuclear Pharmacy Instrumentation.
(3)
Structure and properties of atoms, radiation and radioactive decay, production of radionuclides, interactions of radiation with matter, with emphasis on instrumentation for radiation detection and measurement in a nuclear pharmacy or nuclear medicine environment.
Restriction: permission of instructor.
PHRM 774 / 512.
Radiopharmaceutical Chemistry.
(1)
Introduces undergraduate students to inorganic chemistry as applicable to radiopharmaceuticals.
Prerequisite: CHEM 302.
Restriction: permission of instructor.
PHRM 775.
Radiopharmacy Health and Radiation Biology.
(3)
Fundamentals of the biological effects of ionizing radiation on living systems, especially man; basic biological mechanisms which bring about somatic and genetic effects. Concepts of radiation protection, radiation dosimetry, radiation monitoring and x-ray health physics.
Restriction: permission of instructor.
PHRM 776 / 516.
Radiopharmacology.
(3)
Study of the physicochemical characteristics of radiopharmaceuticals; kinetics of radiopharmaceuticals; structure-distribution relationships of radiopharmaceuticals; considerations in the design of new radiopharmaceuticals.
Restriction: permission of instructor.
PHRM 782.
Clinical Toxicology.
(2)
Study of the acute toxicity in humans of common drugs, chemicals and household products; physical and laboratory assessment of common poisonings; development of clinical management plans and role of pharmacists in prevention of poisonings. P3 standing in College of Pharmacy.
PHRM 783.
Clinical Pharmacy Assessment.
(1)
A self-paced study of laboratory tests used in clinical pharmacy practice.
PHRM 784.
Advanced Infectious Diseases Pharmacotherapy.
(1)
This course will offer an in-depth discussion of the pharmacotherapy on several infectious diseases related topics such as advanced kinetics, MRSA treatment, liver diseases and infections, and HIV.
Prerequisite: 751 with a "C" or higher. Restriction: permission of instructor.
PHRM 785.
Advanced Cardiovascular Pharmacotherapy.
(1)
This course is designed to give students an advanced knowledge and skill base in cardiovascular medicine and will include topics designed to allow the student to maximize the learning experience in the Cardiology APPE.
Restriction: permission of instructor.
PHRM 786.
Geriatric Interprofessional Elective.
(2)
This course involves the study of the treatment of common geriatric disease states in multiple care settings and involves case-based discussion with an interprofessional team of students and instructors. Offered on a CR/NC basis only.
PHRM 798.
Problems in Pharmacy.
(1-5 to a maximum of 10 ?)
Research and library problems in some phases of pharmacy.
Restriction: permission of instructor.
PHRM 799.
Nontraditional Pharm.
(2 to a maximum of 12 ?)
A course for pharmacists with a B.S. degree to receive credit for correspondence and other didactic training toward the Pharm.D. degree. Course must be taken continuously during the didactic training.
Offered on a CR/NC basis only.
NOTE: PHRM 720, 729, 748, 755, 757, 758, 761, 782, 783 and 798 can be used to satisfy the pharmacy professional elective requirements.